3 Keys to Improving Mobility in Parkinson's. RIGHT NOW, not in the future

FORCED EXERCISE, VITAMIN B2 (RIBOFLAVIN) AND NAC (N-ACETYLCYSTEINE, GLUTATHIONE PRECURSOR)

In my opinion three are the keys. There are many more, but I have to keep looking for information.

1) Physical exercise: Alberts (2009).

Intense physical exercise on a static bicycle (especially forced exercise done in tandem with a healthy person) provides an improvement in motor symptoms of around 35-40%, similar to a dose of levodopa (Alberts 2009).

With Forced Exercise (FE) the motor scores on the Unified Parkinson's Disease Rating Scale (UPDRS) improved by 35%, while patients who did Voluntary Exercise (VE) showed no motor improvement (although good for other aspects of health and against Parkinson's).

2) Vitamin B2: Coimbra (2003).

The study focused on administering 30 mg of riboflavin every 8 hours (90 mg per day) and eliminating red meat from the diet for 6 months. There was an improvement in mobility of between 44 and 71%.

Why is riboflavin or vitamin B2 so important in health and Parkinson's? Two words: vitamin B6 and glutathione. It activates vitamin B6 to its coenzyme form that converts levodopa to dopamine, AND helps in the synthesis of glutathione (protects neurons, mitochondria, liver, etc.). In addition, it prevents the risk of Parkinson's disease by 51 % (Powers 1988).

3) NAC (or N-acetylcysteine): Monti (2019)

Weekly intravenous infusion of NAC (50 mg/kg), plus daily oral doses (500 mg twice a day) for 3 months. There was an increase in DAT (dopamine transporters) from 3.4% to 8.3% and a significant improvement in Parkinson's symptoms (this study sheds more light on Dr. Perlmutter's impressive videos of intravenous glutathione, available on the Internet).

We know that the level of magnesium (Barbiroli 1999), glutathione (Sechi 1996), and the neurotoxic homocysteine (Yasui 2000, Muller 2001) largely determine the severity of symptoms and duration of the disease. IT HAS TO BE READ A HUNDRED TIMES.

Magnesium treonate (the only known form of magnesium that crosses the blood-brain barrier or any other form such as chloride or citrate, NAC (or N-acetylcysteine, the precursor to glutathione) and vitamins B6, B9 and B12, which are able to control the level of homocysteine in two different ways, could be key.

NOTE: Although you should always consult your doctor and pharmacist, it is even more important in the case of other diseases and medications. Remember, courage and caution.

Any form of exercise authorized by the doctor is good, from walking to forced exercise, to dancing, water exercises or tai chi...